cysteine proteinase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6037	E-64	Proteinase inhibitor E 64,E 64,E64	Cysteine Protease , Antibacterial , Autophagy
	E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.
T33852	P 34081	P34081,P-34081
	P 34081 rapidly blocks parasite cysteine proteinase activity in vivo.
T38130	Z-LVG-CHN2	Z-Leu-Val-Gly-diazomethylketone
	The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity agains...
T38116	Fmoc-Ala-Glu-Asn-Lys-NH2	Fmoc-Ala-Glu-Asn-Lys-NH2
	Fmoc-Ala-Glu-Asn-Lys-NH2 is a peptide inhibitor that selectively targets asparagine endopeptidase (AEP) and inhibits the cleavage of amyloid precursor protein (APP). AEP, a pH-controlled cysteine proteinase, plays a cruc...
T74192	Z-Leu-Arg-AMC
	Z-Leu-Arg-AMC, a carboxybenzoyl (Z) leucine derivative featuring a 4-methylcoumarinyl-7-amide (AMC), serves as the active site for the cysteine proteinase trypanopain-Tb in Trypanosoma brucei brucei [1].
T78119	Z-L(D-Val)G-CHN2		HSV
	Z-L(D-Val)G-CHN2, an isoform of Z-LVG-CHN2, serves as a cell-permeable and irreversible inhibitor of cysteine proteinase. This tripeptide derivative emulates a segment of the human cysteine proteinase-binding center and ...
T76162	Stem bromelain
	Stem bromelain (EC 3.4.22.32), a cysteine proteinase from pineapple (Ananas comosus) stem, is a significant type of bromelain known for its fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory properties. I...

Recombinant Proteins

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Expression System：

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Cat No.	Product Name	Species	Expression System
TMPH-03648	Cruzipain Protein, Trypanosoma cruzi, Recombinant (His & Myc)	Trypanosoma cruzi	E. coli
	Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group.; The cysteine protease may...
TMPH-00060	ApNPV Viral cathepsin Protein (His & Myc)	ApNPV	E. coli
	Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. May participate in the degradation of foreign protein expressed by the baculovirus system. ApNPV Vir...
TMPH-00134	AcMNPV Viral cathepsin Protein (His & SUMO)	AcMNPV	E. coli
	Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. Accumulates within infected cells as an inactive proenzyme (proV-CATH), which is activated by proteo...
TMPH-00821	EP-B2 Protein, Hordeum vulgare, Recombinant (His & SUMO)	Hordeum vulgare	E. coli
	EP-B2 Protein, Hordeum vulgare, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.3 kDa and the accession number is P25250.
TMPJ-00928	Serpin B3 Protein, Human, Recombinant (C-His)	Human	HEK293 Cells
	Serpin B3 Protein, Human, Recombinant (C-His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 41-50 KDa and the accession number is P29508.
TMPJ-00929	Serpin B3 Protein, Human, Recombinant (N-His)	Human	E. coli
	Serpin B3 Protein, Human, Recombinant (N-His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40-55 KDa and the accession number is P29508.
TMPK-01337	3CLpro/3C-like Protease Protein (Q189K), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01346	3CLpro/3C-like Protease Protein (L50F), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01347	3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01335	3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01344	3CLpro/3C-like Protease Protein (L167F), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01336	3CLpro/3C-like Protease Protein (L50F, E166V), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01342	3CLpro/3C-like Protease Protein (A191V), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01340	3CLpro/3C-like Protease Protein (F140A), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01338	3CLpro/3C-like Protease Protein (H172Y), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01343	3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01339	3CLpro/3C-like Protease Protein (S144A), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01341	3CLpro/3C-like Protease Protein (P132H), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01345	3CLpro/3C-like Protease Protein (L50F, E166A, L167F), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01348	3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306)	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPY-02090	Cystatin B Protein, Human, Recombinant (His)	Human	E. coli
	Cystatin-B, also known as CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB and CST6, is a cytoplasm and nucleus protein which belongs to thecystatin family. Cystatin-B / CSTB is an intracellular thiol proteinas...
TMPJ-00025	CST7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CST7 is a secreted protein and primarily expressed in peripheral blood cells and spleen.It is belongs to the cystatin family. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. S...
TMPJ-01174	Cystatin B Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Cystatin B, also called stefin B or liver thiol proteinase inhibitor, is a member of family 1 of the cystatin superfamily. Like Cystatin A, it is an intracellular inhibitor regulating the activities of cysteine proteases...
TMPJ-01449	3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant	SARS-CoV-2	E. coli
	The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precur...
TMPH-03156	Lys-gingipain Protein, Porphyromonas gingivalis, Recombinant (His & SUMO)	Porphyromonas gingivalis	E. coli
	Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the fun...
TMPY-02077	Cystatin A Protein, Human, Recombinant (His)	Human	E. coli
	Cystatin-A, also known as Cystatin-AS, Stefin-A and CSTA, is a cytoplasm protein which belongs to thecystatin family. Cystatin-A / CSTA is a cysteine proteinase inhibitor with a molecular mass of 11 kDa, and is locate...
TMPH-03154	Lys-gingipain 381 Protein, Porphyromonas gingivalis, Recombinant (His)	Porphyromonas gingivalis	E. coli
	Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the fun...
TMPJ-01448	3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His)	2019-nCoV	E. coli
	The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precur...
TMPH-03155	Lys-gingipain HG66 Protein, Porphyromonas gingivalis, Recombinant (His & Myc)	Porphyromonas gingivalis	E. coli
	Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the fun...
TMPY-00163	SPINK2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Human serine proteinase inhibitor Kazal-type 2 (SPINK2) functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein ...
TMPY-02070	Cystatin SN Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cystatin-SN, also known as Cystain-SA-I, Cystatin-1, Salivary cystatin-SA-1 and CST1, is a secreted protein which belongs to thecystatin family. The cystatin superfamily encompasses proteins that contain multiple cyst...
TMPY-01645	Cystatin SA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cystatin-SA, also known as Cystatin-2, Cystatin-S5 and CST2, is a secreted protein which belongs to thecystatin family. Cystatin-2 / CST2 is expressed in submandibular and sublingual saliva but not in parotid saliva (...
TMPJ-00497	CTSB Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, bot...
TMPY-01644	Cystatin S Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cystatin-S, also known as Cystatin-4, Salivary acidic protein 1, Cystatin-SA-III and CST4, is a secreted protein which belongs to thecystatin family. Cystatin-4 / CST4 is expressed in submandibular and sublingual sali...
TMPY-01249	Cathepsin V Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and t...
TMPY-01824	Caspase-14 Protein, Human, Recombinant (His)	Human	E. coli
	Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses...